Is This The Cure For Alzheimer's Disease ? "?

" Is This The Cure For Alzheimer's Disease ? "





Letters In The Alphabet Of Life :





http://www.vanderbilt.edu/exploration/ne...





DNA :





DNA (deoxyribonucleic acid) is the master molecule of heredity.





It is made up of two strands linked together by four bases in the


form of a double helix. Each strand of DNA is made up of a


backbone and bases that are strung in a precise order.





The two strands of DNA come together like a zipper.


The teeth, or bases, on one side of the zipper match with the


corresponding bases on the other side.





The bases are the nucleic acids adenine (A), guanine (G),


cytosine (C), and thiamine (T).





Adenine and thiamine always pair together,


as do guanine and cytosine. The four bases are the letters


in the alphabet of life.


Visualizing Chemistry In The Human Brain :


http://books.nap.edu/openbook.php?record...





Imaging Brain Amyloid In Alzheimer's Disease With Pittsburgh Compound-B :


http://www3.interscience.wiley.com/cgi-b...





Abstract


This report describes the first human study of a novel amyloid-imaging positron emission tomography (PET) tracer, termed Pittsburgh Compound-B (PIB), in 16 patients with diagnosed mild AD and 9 controls. Compared with controls, AD patients typically showed marked retention of PIB in areas of association cortex known to contain large amounts of amyloid deposits in AD. In the AD patient group, PIB retention was increased most prominently in frontal cortex (1.94-fold, p = 0.0001). Large increases also were observed in parietal (1.71-fold, p = 0.0002), temporal (1.52-fold, p = 0.002), and occipital (1.54-fold, p = 0.002) cortex and the striatum (1.76-fold, p = 0.0001). PIB retention was equivalent in AD patients and controls in areas known to be relatively unaffected by amyloid deposition (such as subcortical white matter, pons, and cerebellum). Studies in three young (21 years) and six older healthy controls (69.5 ± 11 years) showed low PIB retention in cortical areas and no significant group differences between young and older controls. In cortical areas, PIB retention correlated inversely with cerebral glucose metabolism determined with 18F-fluorodeoxyglucose. This relationship was most robust in the parietal cortex (r = -0.72; p = 0.0001). The results suggest that PET imaging with the novel tracer, PIB, can provide quantitative information on amyloid deposits in living subjects.


Received: 9 September 2003; Revised: 4 November 2003; Accepted: 18 November 2003





Inhibitors And Disassemblers Of Fibrillogenesis :


http://www.upstate.com/browse/pgl.q.filt...








http://www.freepatentsonline.com/2003013...





Methods and compositions are presented that inhibit fibril formation and/or bring about disassembly of pre-formed fibrils. Compositions include peptides with short .beta.-strands with two faces: one that can bind to .beta.-amyloids through hydrogen bonds, and one which blocks propagation of hydrogen bonding needed to form fibrils. Thus, short congeners of the fibril protein containing N-methyl amino acids or esters are provided for the inhibition of fibril formation and for the disassembly of pre-existing or pre-formed fibrils. Specific aspects address .beta.-amyloid fibrils; prion mediated fibrils; Huntington protein fibrils. Methods for screening for potential fibril inhibitors and disassemblers, diagnostic analysis and treatments are provided.





" Summary "





The bases are the nucleic acids adenine (A), guanine (G),


cytosine (C), and thiamine (T).





By controlling the natural selection of these primary bases; the above findings, can be processed into a curative therapeutic regime, for a devastating disease entity, known as Alzheimer's Disease.





We have our diagnostic tools, now let us utilize them, and reverse this syndrome, of negative pathological changes.





nana4141

Is This The Cure For Alzheimer's Disease ? "?
You didnt really ask a question, did you?





So, yes. Its the cure! Hurray!